Osteoporosis primarily affects which demographic?

Osteoporosis is a condition characterized by weakened bones, making them more susceptible to fractures. The demographic most commonly affected by osteoporosis is postmenopausal women. This susceptibility is primarily due to hormonal changes that occur during menopause, particularly the reduction in estrogen levels. Estrogen plays a crucial role in maintaining bone density, and its decline accelerates bone resorption (the process where bone is broken down) while reducing bone formation.

As a result, postmenopausal women experience a significant decrease in bone density, which increases their risk of developing osteoporosis. While osteoporosis can occur in men and individuals of various ages, the marked prevalence in postmenopausal women is well-documented in medical literature. Other groups, such as older individuals regardless of sex or those with certain risk factors, can also be affected, but the focus remains on postmenopausal women due to the specific hormonal link.